منابع مشابه
ACTH Regulation of Adrenal SR-B1
The adrenal gland is one of the prominent sites for steroid hormone synthesis. Lipoprotein-derived cholesterol esters (CEs) delivered via SR-B1 constitute the dominant source of cholesterol for steroidogenesis, particularly in rodents. Adrenocorticotropic hormone (ACTH) stimulates steroidogenesis through downstream actions on multiple components involved in steroidogenesis. Both acute and chron...
متن کامل[Concerning the significance of paraoxonase-1 and SR-B1 genes in atherosclerosis].
High-density lipoprotein (HDL) is an independent protective factor against cardiovascular disease. The enzyme paraoxonase-1 (PON-1) contributes to the anti-atherogenic effects of HDL. In vitro studies have demonstrated that paraoxonase's substrates are highly heterogeneous and that some contribute to the development of atherosclerotic lesions. The atheroprotective role of PON-1 was established ...
متن کاملTargeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging
Malignant tumors display remarkable heterogeneity to the extent that even at the same tissue site different types of cells with varying genetic background may be found. In contrast, a relatively consistent marker the scavenger receptor type B1 (SR-B1) has been found to be consistently overexpressed by most tumor cells. Scavenger Receptor Class B Type I (SR-BI) is a high density lipoprotein (HDL...
متن کاملChronic Moderate Alcohol Intakes Accelerate SR-B1 Mediated Reverse Cholesterol Transport
Cholesterol is essential for all animal life. However, a high level of cholesterol in the body is strongly associated with the progression of various severe diseases. In our study, the potential involvement of alcohol in the regulation of high density lipoprotein (HDL) receptor scavenger receptor class B and type I (SR-B1)-mediated reverse cholesterol transport was investigated. We separated ma...
متن کاملAu103(SR)45, Au104(SR)45, Au104(SR)46 and Au105(SR)46 nanoclusters.
High resolution ESI mass spectrometry of the "22 kDa" nanocluster reveals the presence of a mixture containing Au103(SR)45, Au104(SR)45, Au104(SR)46, and Au105(SR)46 nanoclusters, where R = -CH2CH2Ph. MALDI TOF MS data confirm the purity of the sample and a UV-vis spectrum shows minor features. Au102(SC6H5COOH)44, whose XRD crystal structure was recently reported, is not observed. This is due t...
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ژورنال
عنوان ژورنال: médecine/sciences
سال: 2019
ISSN: 0767-0974,1958-5381
DOI: 10.1051/medsci/2019123